CD4/CD8 Cell Ratios in Individuals with Acute and Early HIV Infection

Martin Hoenigl, MD
Assistant Research Scientist at the Antiviral Research Center
University of California San Diego (UCSD), San Diego, CA



CME VIDEOTop of page

About the Presenter: Top of page

Martin Hoenigl is an Assistant Research Scientist in the Department of Medicine, Division of Infectious Diseases, at the University of California, San Diego (UCSD). Before joining UCSD in June 2014, Martin Hoenigl has been an infectious diseases and internal medicine fellow at the Medical University of Graz, Austria, with a research focus on fungal diagnostics and clinical pharmacology of antimycotic drugs. Since joining UCSD, his research focus is acute and early HIV infection and HIV prevention. He conducts translational clinical research focused on prevention and treatment of acute and very recent HIV infection, and - as a PI of two recently funded projects (CFAR Developmental Grant and TMARC pilot study) and an IRFN trainee – an increasing focus on NeuroAIDS. To date, he is author to 101 Pub Med listed publications in the field of infectious diseases, the majority in leading authorship roles.

Learning Objectives: Top of page

At the completion of this educational session, learners will:
  • Know that low CD4/CD8 ratios in HIV infection are associated with higher risk of non-AIDS-related morbidity and mortality.
  • Understand the dynamic of CD4/CD8 ratios during acute and early HIV infection.
  • Appreciate how immediate/early ART initiation may positively influence this dynamic, and reduce the risk of non-AIDS morbidity and mortality.

CME Information: Top of page


This CME activity was approved for AMA PRA Category 1 Credit™ on November 15, 2016 and will terminate November 14, 2019.

The target audience is all physicians, NPs and PAs involved or interested in HIV education.

This online video and post-activity evaluation are one hour in length.
  • After you complete the video portion of this educational activity there will be a post-activity evaluation and quiz.
  • You must achieve at least 70% correct to receive your CME certificate.
  • If successful, you will be provided instructions to print your CME certificate at the completion of this activity.
  • Accreditation Statement: Top of page


    This activity has been planned and implemented in accordance with the accreditation requirements and policies of the of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the Medical Society of the State of New York (MSSNY) and the Physicians’ Research Network (PRN). MSSNY is accredited by the ACCME to provide continuing medical education for physicians.

    The Medical Society of the State of New York designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with extent of their participation in the activity.

    Disclosure Statement: Top of page


    Policies and standards of MSSNY require that speakers and planners for CME activities disclose any relevant financial relationships they may have with commercial interests whose products, devices or services may be discussed in the content of a CME activity.
  • Dr. James Braun (Planner/Course Director) had no relevant financial relationships to disclose.
  • Dr. Hoenigl (Presenter) had no relevant financial relationships to disclose. Dr. Hoenigl submitted his slides in advance for adequate peer review, and will support his presentation and clinical recommendations with the best available evidence from the medical literature.
  • Financial Support: Top of page

    This PRN CME activity is funded in part by unrestricted educational grants from: Bristol-Myers Squibb, Gilead Sciences, Merck & Co, and ViiV Healthcare.

    How to Obtain CME Credit: Top of page

    To obtain CME credit for this PRN program, please visit the PRN Video Channel at the Clinical Education Initiative (CEI) web site. PRN and the Medical Society of the State of New York (MSSNY) jointly sponsor PRN enduring materials for CME, and provide them at no cost to the AIDS Institute of the New York State Department of Health (NYSDOH) for broadcast through the CEI. We thank the NYSDOH for making our CME programs available to a wider audience, and hope you will also browse the many other educational opportunities offered by the CEI.

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