Since 1990, helping busy clinicians master the science and art of caring for people with HIV disease.

The PRN Notebook

Upcoming Events
  • Nov 19 2024 @ 7:00 PM - 1) HPV-positive Oropharyngeal Cancer and 2) Targeting Inflammation in Treated HIV, version 3.0

    HPV-positive Oropharyngeal Cancer: Pathogenesis, Epidemiology, Prevention, Diagnosis and Treatment

    Anil K. Chaturvedi, Ph.D.
    Senior Investigator, Clinical Epidemiology Unit, Clinical Genetics Branch
    Senior Advisor for Faculty Development
    Division of Cancer Epidemiology and Genetics
    National Cancer Institute, National Institutes of Health
    Rockville, MD

    Scott A. Roof, MD MS
    Assistant Professor
    Director of Clinical Research
    Division of Head and Neck Oncology and Microvascular Surgery
    Department of Otolaryngology - Head and Neck Surgery
    Icahn School of Medicine at Mount Sinai

    You are probably aware that HPV is the most common STI, that HPV-16 is the most common cause of anogenital cancer, and that HPV vaccines are most effective when administered before sexual debut. But we now know that the most common cause of oropharyngeal cancer is also HPV-16, and the risk is 2 to 3 times greater in people with HIV. It is critical that we providers at the primary care level keep up to date on the prevention, early diagnosis, and appropriate specialist referral for the spectrum of HPV-related disease. This presentation by Anil Chaturvedi from the NIH, and Scott Roof from Mount Sinai addresses the epidemiology and impact of oropharyngeal cancer, as well as the clinical signs/symptoms, diagnosis and treatment.

    Targeting Inflammation in Treated HIV, version 3.0

    Peter W. Hunt, MD

    Professor of Medicine, Division of Experimental Medicine, UCSF
    Co-Director of Basic/Translational Sciences, Center for AIDS Research
    San Francisco, CA

    A complex interaction of genetic factors, coinfections, immune activation and chronic inflammation persist throughout the course of HIV disease and contribute to the multimorbidities that complicate the management of our patients as they age. Asymptomatic CMV coinfection seems to be a particularly troublesome cofactor for many PLWH. Peter Hunt from UCSF returns with an update on the most recent research pertinent to understanding these complexities as they relate to aging.

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The PRN Notebook

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TRANSMISSION

Transmission, Diagnosis and the HIV Epidemic

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PROGRESSION

Pathogenesis and Progression of HIV Disease.

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MANAGEMENT

Treatment, Resistance and Management of HIV/AIDS

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COMPLICATIONS

Complications and Comorbidities

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COINFECTIONS

Coinfections and Opportunistic Infections

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