Drug-drug Interactions in HIV and HCV in an Aging Population

David J. Back, PhD
Professor of Molecular and Clinical Pharmacology
Institute of Translational Medicine, University of Liverpool, UK

CME VIDEOTop of page

About the Presenter: Top of page

David Back is a Professor of Pharmacology at the University of Liverpool and has worked in the area of Pharmacokinetics and drug –drug interactions for more than 35 years. He established the Liverpool HIV Pharmacology Group (LHPG) in 1987 and subsequently the Liverpool group has been at the forefront of pharmacological research of anti-infective drugs, specifically for HIV and HCV. Currently there are numerous ongoing pharmacokinetic, pharmacogenetic and molecular-based studies involving local, national and international collaborations. David has authored ~400 publications. He is a former Editor in chief of the British Journal of Clinical Pharmacology and is on the Editorial Board of numerous journals. He has established several key resources for health care professionals including www.hiv-druginteractions.org and www.hep-druginteractions.org. In 2007 he was awarded the Lilly Prize from the British Pharmacological Society for outstanding contribution to Clinical Pharmacology.

Learning Objectives: Top of page

At the completion of this educational session, learners will:
  • Be aware of basic mechanisms of drug-drug interactions, as well as strategies for management and prevention.
  • Appreciate ‘risky drug interactions’ between HIV drugs, HCV drugs, and other drugs used for associated comorbidities.
  • Predict the likely drug-drug interactions of newer anti-HCV therapies.
  • Distinguish those antiviral drugs most amenable for use in patients with multiple comorbidities from those more challenging to use due to the magnitude of drug interactions.

CME Information: Top of page

This CME activity was approved for AMA PRA Category 1 Credit™ on October 14, 2014 and will terminate October, 2017.

The target audience is all physicians, NPs and PAs involved or interested in HIV education.

This online video and post-activity evaluation are one hour in length.
  • After you complete the video portion of this educational activity there will be a post-activity evaluation and quiz.
  • You must achieve at least 70% correct to receive your CME certificate.
  • If successful, you will be provided instructions to print your CME certificate at the completion of this activity.
  • Accreditation Statement: Top of page

    This activity has been planned and implemented in accordance with the accreditation requirements and policies of the of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the Medical Society of the State of New York (MSSNY) and the Physicians’ Research Network (PRN). MSSNY is accredited by the ACCME to provide continuing medical education for physicians.

    The Medical Society of the State of New York designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with extent of their participation in the activity.

    Disclosure Statement: Top of page

    Policies and standards of MSSNY require that speakers and planners for CME activities disclose any relevant financial relationships they may have with commercial interests whose products, devices or services may be discussed in the content of a CME activity.
  • Dr. James Braun (Planner/Course Director) had no relevant financial relationships to disclose.
  • Dr. Back (Presenter) had the following personal financial relationships in the previous12 months with manufacturers of the products or services that may be presented in this CME activity: Research Support, Advisory Board, Honorarium from AbbVie; Research Support, Speaker’s Bureau, Honorarium from Gilead; Research Support, Speaker’s Bureau, Advisory Board, Honorarium from Janssen, ViiV, and Merck; Research Support from Bristol-Myers Squibb. Dr. Back supported his presentation and clinical recommendations with the best available evidence from the medical literature, and submitted his slides in advance for adequate peer review.
  • Financial Support: Top of page

    This PRN CME activity is funded in part by unrestricted educational grants from: Bristol-Myers Squibb, Gilead Sciences, Janssen Pharmaceuticals, Merck & Co, and ViiV Healthcare.

    How to Obtain CME Credit: Top of page

    To obtain CME credit for this and other PRN programs, please visit the PRN Video Channel at the Clinical Education Initiative (CEI) web site http://www.ceitraining.org/prn-video/. PRN and the Medical Society of the State of New York (MSSNY) jointly sponsor PRN enduring materials for CME, and provide them at no cost to the AIDS Institute of the New York State Department of Health (NYSDOH) for broadcast through the CEI. We thank the NYSDOH for making our CME programs available to a wider audience, and hope you will also browse the many other educational opportunities offered by the CEI.

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