Fighting a Moving Target: SARS-CoV-2 Evolution and Viral Escape in COVID-19

Jonathan Z. Li, MD, MMSc
Assistant Professor of Medicine
Director of the Harvard/Brigham Virology Specialty Laboratory
Director of the Harvard University Center for AIDS Research Clinical Core
Brigham and Women’s Hospital
Harvard Medical School, Cambridge, MA



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About the Presenter:Top of page

Dr. Li is an infectious disease physician-scientist at the Brigham and Women’s Hospital and Harvard Medical School. He leads an active clinical and translational laboratory research program focused on viral detection, reservoirs and resistance, especially within the fields of HIV and COVID-19. Dr. Li is the Director of the Harvard University Virology Specialty Laboratory, the Director of the Harvard University Center for AIDS Research Clinical Core, and a member of the AIDS Clinical Trials Group (ACTG) Executive Committee. He is the protocol virologist for A5401/ACTIV-2 Adaptive Platform Treatment Trial for Outpatients with COVID-19, the protocol Chair of the ACTG A5308 study of ART treatment for HIV-1 controllers, and the Chair of the A5345 study of biomarkers of HIV rebound. Dr. Li also serves as the Deputy Editor for the Infectious Disease Society of America (IDSA) journal Open Forum Infectious Diseases and on the Editorial Advisory Board for the Journal of Infectious Diseases.

Learning Objectives: Top of page

At the completion of this educational session, learners will:

  • Contrast viral evolution in SARS-CoV-2 with other viruses.
  • Compare SARS-CoV-2 persistence versus reinfection.
  • Define novel strains of SARS-CoV-2 and their impact on the epidemic.

Financial Support:Top of page

This PRN CME activity is funded in part by unrestricted educational grants from: Gilead Sciences; Janssen Therapeutics, a division of Janssen Products, LP; Merck & Co.; and ViiV Healthcare

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