What Is It with HIV-2?
François Clavel, MD
Head, Virus Genetics and Pathogenesis Laboratory
French Institute of Health and Medical Research
Hôpital Saint Louis, Paris, FR
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François Clavel received his M.D. from Necker Medical School in Paris, France. After his residency, he moved to Institut Pasteur where he was involved in the discovery and early characterization of HIV-2. He subsequently worked at NIH, went back to Institut Pasteur and started his own lab at Hôpital Bichat in Paris. He is now head of the Viral Genetics and Pathogenesis Unit at Hôpital Saint Louis, Paris. François Clavel has always been interested in virus genetics, virus evolution and virus fitness. He has spent many years describing the mechanisms of selection and evolution of HIV drug resistance. More recently, his lab has worked on HIV evolution in response to immune pressure and in response to host-specific antiviral barriers.
At the completion of this educational session, learners will:
- Understand the main genetic and pathogenic differences between HIV-1 and HIV-2.
- Appreciate the potential host- and virus-related mechanisms through which HIV-2 replication may be restricted in humans, making HIV-2 an interesting model for studying HIV pathogenesis.
- Know how HIV-2 infection is diagnosed, managed and treated.
This PRN CME activity is funded in part by unrestricted educational grants from:
Bristol-Myers Squibb, Gilead Sciences, Janssen Pharmaceuticals, Merck & Co, and ViiV Healthcare.
