A Closer Look at HIV and Antibody-Based Interventions for Prevention, Treatment, and Cure

Thomas J. Hope, PhD
Professor, Departments of Cell and Molecular Biology
Obstetrics and Gynecology, and Biomedical Engineering
Feinberg School of Medicine
Northwestern University, Chicago, IL



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About the Presenters:Top of page

Thomas J. Hope received his Ph.D. from the University of California, Berkeley, Department of Immunology, where he studied Molecular Immunology under Dr. H. Sakano. He completed his postdoctoral training at the University of California, San Francisco where he studied the HIV Rev protein. Dr. Hope’s laboratory at Northwestern University has pioneered the use of cell biology approaches to study HIV providing images and movies of HIV interacting with cells and tissues. For the past 25 years, his research has focused on HIV Cellular Virology. More recently, this focus has expanded to HIV related mucosal immunology, HIV transmission, and HIV prevention science. His work has been published over the past three decades in respected journals such as Science, PNAS, The Journal of Cell Biology, Cell Host and Microbes, Journal of Virology, and PLoS Pathogens. Dr. Hope is also the Editor-in-Chief of AIDS Research and Human Retroviruses and a Section Editor for PLoS Pathogens. Dr. Hope is a widely respected speaker and gives talks about his innovative work on AIDS/HIV at many institutions and conferences, nationally and internationally.

Learning Objectives: Top of page

At the completion of this educational activity learners will:
1. Appreciate the focal nature of HIV infection and tissue reservoirs.
2. Increase understanding of the virus and its likely ongoing expression during periods of supposed latency.
3. Be aware of the complexities of antibody distribution and cycling in the context of human anatomy and physiology.
4. Gain insights into the advantages and disadvantages of utilizing broadly neutralizing antibodies for HIV prevention, treatment, and cure.

Disclosure Statement:Top of page

Policies and standards of the Medical Society of the State of New York and the Accreditation Council for Continuing Medical Education require that speakers and planners for continuing medical education activities disclose any relevant financial relationships they may have with commercial interests whose products, devices, or services may be discussed in the content of a CME activity.
- Dr. James F. Braun (Course Director/Planner) has no relevant financial relationships to disclose.
- Dr. Joseph P. McGowan (Moderator) has no relevant financial relationships to disclose.
- Dr. Thomas J. Hope (Presenter) has no relevant financial relationships to disclose. Dr. Hope submitted his slides in advance for adequate peer review and supported his presentation and clinical recommendations with the best available evidence from the medical literature.

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