Treatment Challenges of Multi-Drug Resistant HIV-1 Infection

M. Ali Rai, MD, PhD
Principal Investigator
Laboratory of Immunoregulation
National Institute of Allergy and Infectious Diseases
Bethesda, MD

Videos of live meetings of PRN in NYC are owned and published by Physicians’ Research Network, Inc. Copyright © 2023. All rights reserved.



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How to Obtain CME Credit:Top of page

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About the Presenter:Top of page

Dr. Rai earned a Bachelor of Medicine, Bachelor of Surgery (M.B.,B.S.) from Aga Khan University Medical College in Karachi where he helped to identify and shed light on the HIV situation in Pakistan. After completing medical school, he joined Prof. Andrew McMichael and Prof. Sarah Rowland-Jones at the Weatherall Institute of Molecular Medicine at Oxford as a Rhodes Scholar to study immune corelates of protection in a cohort of long-term non-progressors analyzing HLA, T-cell, ADCC and ADCVI responses. After completing his D.Phil. in Clinical Medicine, he became a part of the Physician Scientist Training Program at the University of Cincinnati where he completed his residency in Internal Medicine, followed by a fellowship in Infectious Diseases. He was faculty at the University of Cincinnati prior to moving over to NIAID, NIH in 2021. Dr Rai’s research focus is on HIV Multi-Drug resistance, and he is currently the Principal Investigator for Protocol 22-1-0008: A Single arm Open Label Phase 2 trial of anti-CD4 Antibody UB-421 in Combination with Optimized Background Antiretroviral Therapy in Patients with Multi-Drug Resistant HIV-1 Infection.

Learning Objectives: Top of page

At the completion of this educational activity learners will:
1. Be aware of the challenge of multi-drug resistant HIV.
2. Understand the testing for determining HIV resistance.
3. Know optimization of novel treatment modalities and treatment landscape trajectory.

CME Information:Top of page


This CME activity has approved for AMA PRA Category 1 Credit™ for September 13, 2023, as a live activity. This activity will also be available as an enduring activity from September 20, 2023, through September 12, 2026.

The target audience is all physicians, NPs and PAs involved or interested in HIV education.

This online video and post-activity evaluation are one hour in length.

Accreditation Statement:Top of page


This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the Medical Society of the State of New York (MSSNY) and the Physicians’ Research Network (PRN). MSSNY is accredited by the ACCME to provide continuing medical education for physicians.

The Medical Society of the State of New York designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

ABIM MOC Recognition Statement:Top of page

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1 Medical Knowledge MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

Disclosure Statement:Top of page

Policies and standards of the Medical Society of the State of New York and the Accreditation Council for Continuing Medical Education require that speakers and planners for continuing medical education activities disclose any relevant financial relationships they may have with commercial interests whose products, devices, or services may be discussed in the content of a CME activity.
- Dr. James F. Braun (Course Director/Planner) has no relevant financial relationships to disclose.
- Dr. Sanjiv S. Shah (Moderator) has no relevant financial relationships to disclose.
- Dr. M. Ali Rai (Presenter) has no relevant financial relationships to disclose. Dr. Rai submitted his slides in advance for adequate peer review and supported his presentation and clinical recommendations with the best available evidence from the medical literature.

Financial Support:Top of page

This PRN CME activity is funded in part by unrestricted educational grants from:
Gilead Sciences; Janssen Therapeutics, a division of Janssen Products, LP; Merck & Co.; and ViiV Healthcare

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