Treatment Challenges of Multi-Drug Resistant HIV-1 Infection
M. Ali Rai, MD, PhD
Principal Investigator
Laboratory of Immunoregulation
National Institute of Allergy and Infectious Diseases
Bethesda, MD
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Dr. Rai earned a Bachelor of Medicine, Bachelor of Surgery (M.B.,B.S.) from Aga Khan University Medical College in Karachi where he helped to identify and shed light on the HIV situation in Pakistan. After completing medical school, he joined Prof. Andrew McMichael and Prof. Sarah Rowland-Jones at the Weatherall Institute of Molecular Medicine at Oxford as a Rhodes Scholar to study immune corelates of protection in a cohort of long-term non-progressors analyzing HLA, T-cell, ADCC and ADCVI responses. After completing his D.Phil. in Clinical Medicine, he became a part of the Physician Scientist Training Program at the University of Cincinnati where he completed his residency in Internal Medicine, followed by a fellowship in Infectious Diseases. He was faculty at the University of Cincinnati prior to moving over to NIAID, NIH in 2021. Dr Rai’s research focus is on HIV Multi-Drug resistance, and he is currently the Principal Investigator for Protocol 22-1-0008: A Single arm Open Label Phase 2 trial of anti-CD4 Antibody UB-421 in Combination with Optimized Background Antiretroviral Therapy in Patients with Multi-Drug Resistant HIV-1 Infection.
At the completion of this educational activity learners will:
1. Be aware of the challenge of multi-drug resistant HIV.
2. Understand the testing for determining HIV resistance.
3. Know optimization of novel treatment modalities and treatment landscape trajectory.
Policies and standards of the Medical Society of the State of New York and the Accreditation Council for Continuing Medical Education require that speakers and planners for continuing medical education activities disclose any relevant financial relationships they may have with commercial interests whose products, devices, or services may be discussed in the content of a CME activity.
- Dr. James F. Braun (Course Director/Planner) has no relevant financial relationships to disclose.
- Dr. Sanjiv S. Shah (Moderator) has no relevant financial relationships to disclose.
- Dr. M. Ali Rai (Presenter) has no relevant financial relationships to disclose. Dr. Rai submitted his slides in advance for adequate peer review and supported his presentation and clinical recommendations with the best available evidence from the medical literature.
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