Towards an HIV Cure: Real Progress And Real Problems
David M. Margolis, MD
Professor of Medicine, Microbiology and Immunology, Epidemiology
Director, Program in Translational Clinical Research, IGHID
University of North Carolina at Chapel Hill, Chapel Hill, NC
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David Margolis’s laboratory has a long history of translational HIV research involving samples donated by HIV-infected volunteers: investigating basic molecular, virological, and immunological phenomenon, and leveraging insights to develop new interventions in HIV disease. Dr. Margolis has studied molecular mechanisms in HIV replication and infection, HIV proviral latency, and defined the role of epigenetic factors in the repression of HIV transcription. He has led diverse, multidisciplinary collaborations that resulted in discovery and publication of high-impact work. He is the principal investigator for CARE (Collaboratory of AIDS Researchers for Eradication), a major new NIH-funded research organization that seeks to develop the tools to bring an HIV cure from the bench to the clinic.
At the completion of this educational session, learners will:
- Be aware of current approaches to HIV eradication.
- Appreciate scientific challenges and unknowns in efforts toward the goal of eradication.
- Understand clinical and ethical challenges in this field.
This PRN CME activity is funded in part by unrestricted educational grants from:
Bristol-Myers Squibb, Gilead Sciences, Janssen Pharmaceuticals, Merck & Co, and ViiV Healthcare.
