Therapeutic Strategies Aimed at Achieving Antiretroviral Drug-Free HIV Remission

Tae-Wook Chun, PhD
Chief, HIV Immunovirology Unit
Earl Stadtman Investigator at NIAID/NIH, Bethesda, MD

CME VIDEOTop of page

About the Presenter: Top of page

Tae-Wook Chun received his Ph.D. from the Biochemistry, Cellular, and Molecular Biology Graduate Program from the Johns Hopkins University School of Medicine where he discovered and characterized latently infected, resting CD4+ T cells in HIV-infected individuals. He then pursued postdoctoral work at the NIH, where he demonstrated that latent HIV reservoir persists in virtually all infected individuals receiving antiretroviral therapy despite effective suppression of plasma viremia, and that early initiation of antiretroviral therapy leads to a decay of the latent viral reservoir. He is currently the Earl Stadtman Investigator at NIAID/NIH and continues to study the role of viral reservoirs in the pathogenesis of HIV disease and is working towards developing therapeutic strategies aimed at achieving sustained virologic remission in infected individuals without antiretroviral therapy.

Learning Objectives: Top of page

At the completion of this educational session, learners will:
  • Understand the impact of analytical treatment interruption on immunologic and virologic parameters in HIV-infected individuals.
  • Know the outcome of recent therapeutic clinical trials aimed at achieving sustained virologic remission in HIV-infected individuals in the absence of antiretroviral therapy.
  • Be aware of an on-going clinical trial being conducted at the National Institute of Allergy and Infectious Diseases involving two HIV-specific broadly neutralizing antibodies.

CME Information: Top of page

This CME activity has approved for AMA PRA Category 1 Credit™ on December 11, 2018 and will terminate December 10, 2021.

The target audience is all physicians, NPs and PAs involved or interested in HIV education.

This online video and post-activity evaluation are one hour in length.
  • After you complete the video portion of this educational activity there will be a post-activity evaluation and quiz.
  • You must achieve at least 70% correct to receive your CME certificate.
  • If successful, you will be provided instructions to print your CME certificate at the completion of this activity.
  • Accreditation Statement: Top of page

    This activity has been planned and implemented in accordance with the accreditation requirements and policies of the of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the Medical Society of the State of New York (MSSNY) and the Physicians’ Research Network (PRN). MSSNY is accredited by the ACCME to provide continuing medical education for physicians.

    The Medical Society of the State of New York designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with extent of their participation in the activity.

    Disclosure Statement: Top of page

    Policies and standards of MSSNY require that speakers and planners for CME activities disclose any relevant financial relationships they may have with commercial interests whose products, devices or services may be discussed in the content of a CME activity.
  • Dr. James Braun (Planner/Course Director) had no relevant financial relationships to disclose.
  • Dr. Tae-Wook Chun (Presenter) had no relevant financial relationships to disclose. Dr. Chun submitted his slides in advance for adequate peer review, and will support his presentation and clinical recommendations with the best available evidence from the medical literature.
  • Financial Support: Top of page

    This PRN CME activity is funded in part by unrestricted educational grants from: Gilead Sciences; Janssen Therapeutics, a division of Janssen Products, LP; and Merck & Co.

    How to Obtain CME Credit: Top of page

    To obtain CME credit for this PRN program, please visit the PRN Courses Page at the Clinical Education Initiative (CEI) web site. PRN and the Medical Society of the State of New York (MSSNY) jointly sponsor PRN enduring materials for CME, and provide them at no cost to the AIDS Institute of the New York State Department of Health (NYSDOH) for broadcast through the CEI. We thank the NYSDOH for making our CME programs available to a wider audience, and hope you will also browse the many other educational opportunities offered by the CEI.

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