Gene Therapy Studies for the Treatment of HIV Infection
Pablo Tebas, MD
Professor of Medicine
Director and Principal Investigator, AIDS clinical trial unit research site
University of Pennsylvania, Philadelphia, PA
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| Learning Objectives for: Gene Therapy Studies for the Treatment of HIV Infection | Top of page |
At the completion of this educational session, participants should be able to:
- Know the different gene therapy approaches that are being taken to treat HIV infection and the role of zinc finger nucleases.
- Discuss the potential side effects of these approaches.
- Understand other potential strategies beyond gene therapy to control HIV in the absence of antiretroviral therapy.
Pablo Tebas directs the adult AIDS Clinical Trials Unit (ACTU) of the University of Pennsylvania. His main research interests are the treatment of HIV infection and the study of the metabolic complications associated with HIV infection and its treatment The introduction of highly active antiretroviral therapy has resulted in significant reductions in the morbidity and mortality associated with HIV infection. Unfortunately, the use of HAART has also been associated with significant adverse effects, including dyslipidemia and insulin resistance, bone disease and fat redistribution. Current studies are directed to understand better the mechanisms of these complications and prevent their development.
Current outpatient and inpatient clinical activities center in the Hospital of the University of Pennsylvania where he follows general ID and HIV infected patients.
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